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ABOUT US

The Collaborative Alliance for Pancreatic Education and Research’s (CAPER) mission is: (a) to facilitate the collaboration of researchers of pancreatic diseases and to support scientifically rigorous multi-center studies in pancreatic diseases; (b) to educate and train healthcare providers in pancreatic diseases; (c) and to increase public health awareness regarding pancreatic diseases.

CONTACT US

1400 N. Harbor Blvd.
Suite 625
Fullerton, CA 92835

O: 714-626-0458
F: 866-735-4373

caper@pacemedcom.com

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CAPER is managed by PACE Medical Communications

© 2019 Collaborative Alliance for Pancreatic Education and Research

APPRENTICE
Acute Pancreatitis Patient Registry to Examine Novel Therapies in Clinical Experiences

What is APPRENTICE?


APPRENTICE is an international multi-center study on Acute Pancreatitis sponsored by CAPER. This study initiated by Georgios Papachristou, MD, Ph.D. Professor of Medicine at the University of Pittsburgh. The idea of creating a prospective international registry in Acute Pancreatitis developed during the PancreasFest 2014  (July 2014, Pittsburgh, PA). The University of Pittsburgh has led this initiative and served as the coordinating center. Dr. Papachristou in collaboration with Amir Gougol, internal medicine resident, designed and conducted the study and invited the investigators from highly experienced centers in pancreatic research. 


In September 2015, the APPRENTICE phase I enrolled the first patient. Regular monthly/bi-weekly webinars, and multiple rounds of data quality monitoring performed under the guidance of Phil Greer, biostatistician, to ensure the quality of data. To date, more than 1500 patients from 24 centers throughout the world prospectively enrolled in the study.  

Should you have any questions, please contact Georgios Papachristou at papachri@pitt.edu,  Amir Gougol at gougolah@upmc.edu, or Phil Greer at pgreer@upmc.edu.

 

Participating Centers

On right, Georgios Papachristou, and on left Amir Gougol
 
Number of enrollment as of June 10th, 2017

APPRENTICE Progress

 

Publications/Grants

 

APPRENTICE Method Paper

Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): an international, multicenter consortium for the study of acute pancreatitis.

Papachristou GI1, Machicado JD1, Stevens T2, Goenka MK3, Ferreira M4, Gutierrez SC5, Singh VK6, Kamal A6, Gonzalez-Gonzalez JA7, Pelaez-Luna M8, Gulla A9, Zarnescu NO10, Triantafyllou K11, Barbu ST12, Easler J13, Ocampo C14, Capurso G15, Archibugi L15, Cote GA16, Lambiase L17, Kochhar R18, Chua T2, Tiwari SC3, Nawaz H19, Park WG20, de-Madaria E21, Lee PJ22, Wu BU23, Greer PJ1, Dugum M1, Koutroumpakis E1, Akshintala V6, Gougol A1.

The method manuscript published in Annals of Gastroenterology and presented in DDW2010

Grant

UPP grant to support central biostatistician

Analysis and Publication Committee

In the webinar held on May 30, it was decided to assemble an “Analysis and Publication Committee”. 

MEMBERS

Vikesh Singh, M.D.

Johns Hopkins Hospital, Baltimore, USA

 

Enrique de-Madaria, M.D.  

Unidad Hospital General Universitario de Alicante, Alicante, Spain

 

Rakesh Kochhar, M.D.

Postgraduate Institute of Medical Education and Research, Chandigarh, India

 

Silvia C. Gutiérrez, M.D.

Hospital Nacional "Profesor A. Posadas", Buenos Aires, Argentina

 

Georgios I.Papachristou, M.D. Ph.D.

University of Pittsburgh, Pittsburgh, USA

 

Authorship Guidelines

 

UPDATED STUDY PROTOCOL 

STUDY CONSENT FORM 

UPMC IRB APPROVAL LETTER

DATA USE AGREEMENT 

Past Webinars:

June 2017

https://www.youtube.com/watch?v=CtGtyc4A8Do&t=1046s